Designgive is a great new site that gives designers an oppurtunity to promote their work and contribute to charities as well. Some great designers are on the initial roster including Brooke Nunez, Scott Bartlett, Sauerkids and Si Scott (who seems to be doing everything at the moment).
If you buy one of the shirts, long sleeve ts, or a hoody are able to choose from a list of charities and a donation from each purchase will be made on your behalf. Additionally, if you are a designer you can get involved in the project too. Oh, the prices are good too.
Seen at: joshspear.com